Publications

We aim to release all our work as pre-prints. This is thus the most up-to-date view of our science. Comments appreciated.

Still unpublished pre-prints:

, T.I., Hansen, L.C., Boesen, T., Olesen, C., Møller, (2020) Histidine-rich Ca²⁺-binding protein stimulates the transport cycle of SERCA through a conformation-dependent fuzzy complex. bioRxiv

Peer-reviewed publications:

Kjaergaard, M., Rasmussen, L.S., Nygaard Vinther, J., Røjkjær Andersen, K., Sloth Andersen, E., Lorentzen, E., Thirup, S.S., Otzen, D.E. & Egeskov Brodersen, D. (2022) A semester-long learning path teaching computational skills via molecular graphics in PyMOL (The Biophysicist) (in press)

Bohr et al. (2022) Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies. Comms. Bio. (in press)

Dyla*, M., Gonzalez Foutel*, N., Otzen, D.E. & Kjaergaard, M. (2022) The optimal docking strength for reversibly tethered kinases. PNAS. 119(25):e2203098119 Video abstract

Kjaergaard, M. (2022) Estimation of Effective Concentrations Enforced by Complex Linker Architectures from Conformational Ensembles Biochemistry. 61(3):171-182.

Kjaergaard, M., Petersen, N.C., Sørensen, J.B. & Takeuchi, T. (2021) Introducing the special issue on “Proteins and Circuits in Memory”. Eur. J. Neurosci. 54(8):6691-6695

Dyla, M. & Kjaergaard M. (2021) Intrinsic disorder in protein kinase A anchoring proteins signaling complexes Prog. Mol. Biol. Trans. Sci. 183:271-294

Jendroszek, A. and Kjaergaard M. (2021) Nanoscale spatial dependence of avidity in an IgG1 antibody. Scientic reports. 11: 12663

Basse Hansen, S., Dyla, M., Neumann, C., Lauwring Andersen, J., Kjaergaard, M. & Nissen, P. (2021) The crystal structure of the Ca²⁺-ATPase 1 from Listeria monocytogenes reveals a pump primed for dephosphorylation. J Mol Biol. 433(16): 167015

Kjaergaard, M., Glavina, J. & Chemes, L.B. (2021) Predicting the effect of disordered linkers on effective concentration and avidity with the “Ceff calculator” app. Method. Enz. 647: 145-171 (Link to web server)

Dyla, M. and Kjaergaard M. (2020) Intrinsically disordered linkers control tethered kinases via effective concentration. PNAS 117(35):21413-21419

Sørensen, C.S. and Kjaergaard M. (2020) Measuring Effective Concentrations Enforced by Intrinsically Disordered Linkers. Methods in Molecular Biology. 2141:505-518

Dear, A.J., Meisl, G., Šarić, A., Michaels, T.C.T., Kjaergaard, M., Linse, S. & Knowles, T.P.J. (2020) Identification of on- and off-pathway oligomers in amyloid fibril formation. Chem. Sci. 11:6236-6247

Warnet, X. L., Bakke Krog, H., Sevillano-Quispe, O. G., Poulsen, H. & Kjaergaard, M. (2020) The C‐terminal domains of the NMDA receptor: How intrinsically disordered tails affect signalling, plasticity, and disease. Eur. J. Neuroscience (in press)

Dyla, M., Kjaergaard, M., Poulsen, H. and Nissen, P. (2020) Structure and Mechanism of P-Type ATPase Ion Pumps. Annu. Rev. Biochem. 89:583-603

Sørensen, C.S. and Kjaergaard M. (2019) Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics. PNAS 116(46), 23124-23131. Highlighted in: PreLights & F1000

Dyla, M., Basse Hansen, S., Nissen, P. and Kjaergaard, M. (2019) Structural dynamics of P-type ATPase ion pumps. Biochem. Soc. Trans. 47(5), 1247-1257

Sørensen, C.S., Jendroszek, A. and Kjaergaard M. (2019) Linker dependence of avidity in multivalent interactions between disordered proteins. J. Mol. Biol. 431 (24), 4784-4795

Karlsson, E., Andersson, E., Jones, N.C., Vrønning Hoffmann, S., Jemth, P. and Kjaergaard, M. (2019) Coupled Binding and Helix Formation Monitored by Synchrotron-Radiation Circular Dichroism. Biophys. J. 117(4):729-742

Dyla M, Terry DS, Kjaergaard M, Sørensen TL, Lauwring Andersen J, Andersen JP, Rohde Knudsen C, Altman RB, Nissen P, Blanchard SC. (2017) Dynamics of P-type ATPase transport revealed by single-molecule FRET. Nature. Nov 16;551(7680):346-351.

Kjaergaard, M. and Kragelund B.B. (2017) Functions of intrinsic disorder in transmembrane proteins. Cell Mol Life Sci. Sep;74(17):3205-3224. Highlighted on F1000

Dyla, M., Andersen, J.L., Kjaergaard, M., Birkedal, V., Terry, D.S., Altman, R.B., Blanchard, S.C., Nissen, P., Knudsen, C.R. (2016) Engineering a Prototypic P-type ATPase Listeria monocytogenes Ca²⁺-ATPase 1 for Single-Molecule FRET Studies. Bioconjug Chem. 2016 21;27(9):2176-87

Kjaergaard, M. (2015) Can a protein be intrinsically disordered inside a membrane? Intrinsically disordered proteins 3(1):1-7

A full publication list including Magnus’s work before moving to Aarhus can be found at ORCID.